Longer and better lives for patients with atrial fibrillation: the 9th AFNET/EHRA consensus conference

EP Europace Journal

9 April 2024
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ESC Journals ARRHYTHMIAS AND DEVICE THERAPY Research Methodology Atrial Fibrillation (AF)

Abstract

AbstractAims

Recent trial data demonstrate beneficial effects of active rhythm management in patients with atrial fibrillation (AF) and support the concept that a low arrhythmia burden is associated with a low risk of AF-related complications. The aim of this document is to summarize the key outcomes of the 9th AFNET/EHRA Consensus Conference of the Atrial Fibrillation NETwork (AFNET) and the European Heart Rhythm Association (EHRA).

Methods and results

Eighty-three international experts met in Münster for 2 days in September 2023. Key findings are as follows: (i) Active rhythm management should be part of the default initial treatment for all suitable patients with AF. (ii) Patients with device-detected AF have a low burden of AF and a low risk of stroke. Anticoagulation prevents some strokes and also increases major but non-lethal bleeding. (iii) More research is needed to improve stroke risk prediction in patients with AF, especially in those with a low AF burden. Biomolecules, genetics, and imaging can support this. (iv) The presence of AF should trigger systematic workup and comprehensive treatment of concomitant cardiovascular conditions. (v) Machine learning algorithms have been used to improve detection or likely development of AF. Cooperation between clinicians and data scientists is needed to leverage the potential of data science applications for patients with AF.

Conclusions

Patients with AF and a low arrhythmia burden have a lower risk of stroke and other cardiovascular events than those with a high arrhythmia burden. Combining active rhythm control, anticoagulation, rate control, and therapy of concomitant cardiovascular conditions can improve the lives of patients with AF.

Contributors

Jason G Andrade
Jason G Andrade

Author

Vancouver General Hospital Vancouver , Canada

Elena Arbelo
Elena Arbelo

Author

Hospital Clinic, University of Barcelona Barcelona , Spain

Giuseppe Boriani
Giuseppe Boriani

Author

Modena Polyclinic Modena University Hospital Modena , Italy

Guenter Breithardt
Guenter Breithardt

Author

University Hospital Munster - UKM Muenster , Germany

A John Camm
A John Camm

Author

City St George's University of London London , United Kingdom of Great Britain & Northern Ireland

Valeria Caso
Valeria Caso

Author

Hospital Santa Maria Della Misericordia Perugia , Italy

Mirko De Melis
Mirko De Melis

Author

Bakken Research Centre Maastricht , Netherlands (The)

Tom De Potter
Tom De Potter

Author

Cardiovascular Research Center Aalst Aalst , Belgium

Wolfgang Dichtl
Wolfgang Dichtl

Author

Innsbruck Medical University Innsbruck , Austria

Søren Zoega Diederichsen
Søren Zoega Diederichsen

Author

Rigshospitalet - Copenhagen University Hospital Copenhagen , Denmark

David Duncker
David Duncker

Author

Hannover Heart Rhythm Center Hannover , Germany

Larissa Fabritz
Larissa Fabritz

Author

University Heart and Vascular Centre Hamburg (UHZ) Hamburg , Germany

Michal Farkowski
Michal Farkowski

Author

Ministry of Interior and Administration National Medical Institute Warsaw , Poland

David Filgueiras-Rama
David Filgueiras-Rama

Author

Spanish National Centre for Cardiovascular Research Madrid , Spain

Eduard Guasch
Eduard Guasch

Author

Hospital Clinic of Barcelona Barcelona , Spain

Karl Georg Haeusler
Karl Georg Haeusler

Author

University Hospital of Ulm Ulm , Germany

Hein Heidbuechel
Hein Heidbuechel

Author

University Hospital Antwerp Edegem , Belgium

Ziad Hijazi
Ziad Hijazi

Author

Uppsala University Uppsala , Sweden

Stefan Kääb
Stefan Kääb

Author

Ludwig Maximilians University Hospital Munich , Germany

Dipak Kotecha
Dipak Kotecha

Author

University of Birmingham Birmingham , United Kingdom of Great Britain & Northern Ireland

Katarzyna Malaczynska-Rajpold
Katarzyna Malaczynska-Rajpold

Author

Royal Brompton and Harefield Hospital Harefield, Uxbridge , United Kingdom of Great Britain & Northern Ireland

José Luis Merino
José Luis Merino

Author

La Paz University Hospital Madrid , Spain

Lluís Mont
Lluís Mont

Author

Hospital Clinic of Barcelona Barcelona , Spain

Ghulam Andre Ng
Ghulam Andre Ng

Author

University of Leicester Leicester , United Kingdom of Great Britain & Northern Ireland

Helmut Puererfellner
Helmut Puererfellner

Author

Ordensklinikum Linz Elisabethinen Linz , Austria

Michiel Rienstra
Michiel Rienstra

Author

University Medical Centre Groningen Groningen , Netherlands (The)

Daniel Scherr
Daniel Scherr

Author

Medical University of Graz Graz , Austria

Renate Schnabel
Renate Schnabel

Author

University Heart and Vascular Centre Hamburg (UHZ) Hamburg , Germany

Christian Sohns
Christian Sohns

Author

Heart and Diabetes Center NRW Bad Oeynhausen , Germany

Isabelle C van Gelder
Isabelle C van Gelder

Author

University Medical Centre Groningen Groningen , Netherlands (The)

Paulus Kirchhof
Paulus Kirchhof

Author

University Heart and Vascular Centre Hamburg (UHZ) Hamburg , Germany

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