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Identification of cell-intrinsic effects of mutated circulating cells due to clonal hematopoiesis in patients with heart failure

25 August 2023 (07:30 - 18:30)
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Congress Presentation Part of: Ageing, clonal, haematopoiesis and senescence Leukocytes, Inflammation, Immunity ESC Professional Premium Access ESC Congress 2023 European Society of Cardiology

About the speaker

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Assistant Professor Wesley Abplanalp

J. W. Goethe University Frankfurt, Frankfurt (Germany)

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The senolytic agent Dasatinib reduces fat accumulation in the heart and bone marrow of type 2 diabetic, obese mice and adipogenesis of human bone marrow pericytes
Ms Y. Gu (Bristol, GB)
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Hyperglycemia epigenetically propels senescence-associated secretory phenotype of CD34 hematopoietic stem cells and their myeloid expansion into inflammatory monocyte subpopulations
Doctor G. Damiano (Milan, IT)
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Canagliflozin enhances endogenous eliminatiton of senescent cells through downregulation of PD-L1
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Ageing, clonal, haematopoiesis and senescence

The Event

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ESC Congress 2023

25 August - 28 August 2023

ESC 365 is supported by

novartis Explore sponsored resources

ESC 365 is supported by

novartis Explore sponsored resources