Speaker illustration

Assistant Professor Wesley Abplanalp

Wolfgang Goethe University, Frankfurt (Germany)

Member of:

European Society of Cardiology

ScRNA-seq and flow cytometry based analysis reveals that chronic heart failure associates with enhanced activation and clonal expansion of T cells with predictive autoreactive capacity

Event: ESC Congress 2023

Topic: Heart Failure

Session: Novel pathomechanisms identified by single-cell technologies

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Hematopoietic loss of Y-chromosome in monocytes from heart failure patients associates with cardiac fibrosis signaling

Event: ESC Congress 2023

Topic: Leukocytes, Inflammation, Immunity

Session: Immune mechanisms in myocardial diseases

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Prevalently carried HLA allele associates with inflammation and poor prognosis in HF patients via co-stimulatory, adhesion and MHC-II enhanceosome regulation

Event: ESC Congress 2023

Topic: Leukocytes, Inflammation, Immunity

Session: Macrophages and inflammation

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Aortic valve calcification is promoted by clonal hematopoiesis associated with DNMT3A and TET2 gene driver mutations

Event: ESC Congress 2023

Topic: Valvular Heart Disease

Session: Novel insights into aortic valve disease

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Identification of cell-intrinsic effects of mutated circulating cells due to clonal hematopoiesis in patients with heart failure

Event: ESC Congress 2023

Topic: Leukocytes, Inflammation, Immunity

Session: Ageing, clonal, haematopoiesis and senescence

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DNMT3A clonal hematopoiesis-driver mutations are associated with profound changes in monocyte and T cell signatures in humans with heart failure

Event: ESC Congress 2020

Topic: Leukocytes, Inflammation, Immunity

Session: Basic Science Cardiac ePosters

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Single cell RNA sequencing reveals profound changes in monocytic cell clusters in patients with mutations associated with clonal hematopoiesis

Event: ESC Congress 2019

Topic: Leukocytes, Inflammation, Immunity

Session: Immune modulation in cardiovascular disease

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