The senolytic agent Dasatinib reduces fat accumulation in the heart and bone marrow of type 2 diabetic, obese mice and adipogenesis of human bone marrow pericytes

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The senolytic agent Dasatinib reduces fat accumulation in the heart and bone marrow of type 2 diabetic, obese mice and adipogenesis of human bone marrow pericytes

Session: Ageing, clonal, haematopoiesis and senescence

Topic: Lipid Metabolism, Metabolic Syndrome, Diabetes

Speaker: Ms Y. Gu (Bristol, GB)

Event: ESC Congress 2023

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Ms Yue Gu

University of Bristol, Bristol (United Kingdom of Great Britain & Northern Ireland)

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4 more presentations in this session

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Hyperglycemia epigenetically propels senescence-associated secretory phenotype of CD34 hematopoietic stem cells and their myeloid expansion into inflammatory monocyte subpopulations

Speaker: Doctor G. Damiano (Milan, IT)

Canagliflozin enhances endogenous eliminatiton of senescent cells through downregulation of PD-L1

Speaker: Doctor G. Katsuumi (Tokyo, JP)

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Ageing, clonal, haematopoiesis and senescence

Speakers: Ms Y. Gu, Professor C. Yeh, Assistant Professor W. Abplanalp, Doctor G. Damiano, Doctor G. Katsuumi

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ESC Congress 2023

25 August - 28 August 2023

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