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The senolytic agent Dasatinib reduces fat accumulation in the heart and bone marrow of type 2 diabetic, obese mice and adipogenesis of human bone marrow pericytes

25 August 2023 (09:15 - 09:50)
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Congress Presentation Part of: Ageing, clonal, haematopoiesis and senescence Lipid Metabolism, Metabolic Syndrome, Diabetes ESC Professional Premium Access ESC Congress 2023 European Society of Cardiology

About the speaker

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Ms Yue Gu

University of Bristol, Bristol (United Kingdom of Great Britain & Northern Ireland)

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Elevation of CISD2 attenuates atrial aging
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Identification of cell-intrinsic effects of mutated circulating cells due to clonal hematopoiesis in patients with heart failure
Assistant Professor W. Abplanalp (Frankfurt, DE)
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Hyperglycemia epigenetically propels senescence-associated secretory phenotype of CD34 hematopoietic stem cells and their myeloid expansion into inflammatory monocyte subpopulations
Doctor G. Damiano (Milan, IT)
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Canagliflozin enhances endogenous eliminatiton of senescent cells through downregulation of PD-L1
Doctor G. Katsuumi (Tokyo, JP)
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Ageing, clonal, haematopoiesis and senescence

The Event

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ESC Congress 2023

25 August 2023 09:15 CET

ESC 365 is supported by

novartis Explore sponsored resources

ESC 365 is supported by

novartis Explore sponsored resources