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RKER-012, a novel modified ActRIIB ligand trap, attenuated right ventricular cardiomyopathy in a preclinical model of pulmonary arterial hypertension.

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Mr Pritesh Jain

Keros Therapeutics, Lexington (United States of America)
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Doctor Keith Babbs

(United States of America)
1 presentation
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CS585, a novel prostacyclin receptor agonist, demonstrates sustained efficacy in vivo in the prevention of thrombosis

Speaker: Professor M. Holinstat (Ann Arbor, US)

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First-in-human study to evaluate the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of RBD4059, a GalNAc-siRNA drug targeting coagulation factor XI (FXI), in healthy subjects

Speaker: Doctor A. Gabrielsen (Gothenburg, SE)

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Preclinical characterisation and first-in-human results on the tolerability and pharmacodynamic effect of REGN9933, a monoclonal antibody targeting the factor XI/activated factor XI apple 2 domain

Speaker: Doctor A. Kithcart (US)

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Phase I results of both IV and oral administration for CG-0255: a novel fast-acting antiplatelet drug with a new activation pathway

Speaker: Doctor X. Chen (Shanghai, CN)

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Developing p21-activated kinase 1 (PAK1) activators to treat hypertrophic cardiomyopathy (HCM)

Speaker: Miss Y. He (Oxford, GB)

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Access the full session

Biotherapies in cardiovascular disease: from bench to bedside

Speakers: Mr P. Jain, Doctor K. Babbs, Professor M. Holinstat, Doctor A. Gabrielsen, Doctor A. Kithcart...
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ESC Congress 2024

30 August - 2 September 2024

Sessions Presentations