ESC 365 - The small conductance Ca2+-activated K+-channel inhibition tool compound AP14145 protected the guinea pig heart from ventricular arrhythmia during hypokalemia whereas dofetilide was pro-arrhythmic

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The small conductance Ca2+-activated K+-channel inhibition tool compound AP14145 protected the guinea pig heart from ventricular arrhythmia during hypokalemia whereas dofetilide was pro-arrhythmic

Session: Poster Session 1 - Preclinical pharmacotherapy

Topic: Antiarrhythmic Pharmacotherapy

Speaker: Professor M. Grunnet (Copenhagen N, DK)

Event: ESC Congress 2019

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Professor Morten Grunnet

Copenhagen N (Denmark)

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8 more presentations in this session

The KCa2 channel inhibitor AP14145, but not dofetilide or ondansetron, provides functional atrial selectivity in guinea pig hearts

Speaker: Associate Professor N. Edvardsson (Gothenburg, SE)

Mechanisms of action of the small conductance Ca2+-activated K+-channel modulator AP30663, a novel compound being developed for treatment of atrial fibrillation in man

Speaker: Mrs S. Bomholtz (Copenhagen N, DK)

The SK channel inhibitor AP30663, converts vernakalant-resistant persistent AF and prevents its reinduction in pigs

Speaker: Doctor J. Diness (Copenhagen, DK)

The role of a phosphoinositide-3 kinase inhibitor in vascular inflammation

Speaker: Miss H. Chaudhry (London, GB)

Anti-thrombin nanoparticles for reduce vascular damage and promote functional recovery in acute ischemic kidney injury well after reperfusion

Speaker: Associate Professor H. Pan (Saint Louis, US)

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Poster Session 1 - Preclinical pharmacotherapy

Speakers: Professor M. Grunnet, Associate Professor N. Edvardsson, Mrs S. Bomholtz, Doctor J. Diness, Miss H. Chaudhry...

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ESC Congress 2019

31 August - 4 September 2019

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