Exercise training for cardiovascular prevention in patients with cancer A scientific statement of the Heart Failure Association, the European Association of Preventive Cardiology of the ESC, and the ESC Council of Cardio-Oncology

European Heart Journal

15 July 2026
Organised by: Logo
ESC Journals OTHER European Society of Cardiology

Abstract

Abstract

Patients with cancer usually report limitations of their functional capacity, which may range from subclinical impairment of cardiopulmonary exercise reserve to poor quality of life with physical, cognitive, or psychosocial consequences. Exercise training is a potent multi-targeted approach to control pre-existing and new risk factors. Preliminary evidence shows that it is associated with a lower risk of cancer therapy-related cardiotoxicity and increased self-reported well-being in patients with cancer. Current evidence demonstrates that supervised exercise therapy, including high-intensity interval training, is safe and well-tolerated and reduces risk in subjects with cancer in the pre-, active-, and post-treatment settings. The present consensus document will discuss the role of exercise training in cardio-oncology, focusing on patients with cardiovascular diseases induced by cancer treatment and on those who received cardiotoxic therapies.

Contributors

Massimo Piepoli
Massimo Piepoli

Author

IRCCS San Donato Polyclinic San Donato Milanese , Italy

Markus S Anker
Markus S Anker

Author

Charité - University Medicine Berlin Berlin , Germany

Lorenz H Lehmann
Lorenz H Lehmann

Author

University Hospital Heidelberg Heidelberg , Germany

Emeline Van Craenenbroeck
Emeline Van Craenenbroeck

Author

University Hospital Antwerp Edegem , Belgium

Kalliopi Keramida
Kalliopi Keramida

Author

Agios Savvas General Oncology Hospital Athens , Greece

Antoni Bayes-Genis
Antoni Bayes-Genis

Author

University Hospital Germans Trias and Pujol de Badalona Badalona , Spain

David Niederseer
David Niederseer

Author

Hochgebirgsklinik Davos Davos Wolfgang , Switzerland

Zaza Iakobishvili
Zaza Iakobishvili

Author

Holon Medical Center Tel Aviv , Israel

Yvonne Koop
Yvonne Koop

Author

University Medical Center Utrecht Utrecht , Netherlands (The)

Aaron Sverdlov
Aaron Sverdlov

Author

University of Newcastle Newcastle , Australia

Hadi Skouri
Hadi Skouri

Author

balamand university Beirut , Lebanon

Teresa Lopez-Fernandez
Teresa Lopez-Fernandez

Author

La Paz University Hospital Madrid , Spain

Dimitrios Farmakis
Dimitrios Farmakis

Author

National & Kapodistrian University of Athens Athens , Greece

Ovidiu Chioncel
Ovidiu Chioncel

Author

Oslo University Hospital Rikshospitalet Oslo , Norway

Andrew J S Coats
Andrew J S Coats

Author

Heart Research Institute Sydney , Australia

Marco Metra
Marco Metra

Author

IRCCS San Raffaele Scientific Institute Milan , Italy

Carlo G Tocchetti
Carlo G Tocchetti

Author

University of Naples Federico II Naples , Italy

Maurizio Volterrani
Maurizio Volterrani

Author

IRCCS San Raffaele Rome , Italy