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Prostaglandin E2-EP2 signalling drives vascular aging by inducing mitochondrial dysfunction and pro-inflammatory phenotypic switching via QSOX1 up-regulation

28 August 2026 (13:27 - 13:39)
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Congress Presentation Part of: Endothelial dysfunction, senescence, and vascular ageing Stem Cells, Cell Cycle, Cell Senescence, Cell Death ESC Professional Premium Access ESC Congress 2026 European Society of Cardiology

About the speaker

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Doctor James Jiqi Wang

Tongji Hospital- Tongji Medical College, Wuhan (China)

4 More presentations in this session

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Chromatin readers orchestrate doxorubicin-induced endothelial senescence and paracrine cardiotoxicity: towards epi-drugs in cardio-oncology
Doctor S. Mohammed (Zurich, CH)
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An age-associated microRNA regulates angiogenic capacity and inflammatory signaling in endothelial senescence
Doctor K. Kalies (Halle, DE)
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Single-cell analysis reveals inter-organ endothelial crosstalk in aging and obesity
Assistant Professor M. Yokoyama (Chiba, JP)
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Endothelial GPR146 promotes blood pressure elevation by impairing endothelium-dependent vasodilation
Doctor S. Liu (Beijing, CN)
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Endothelial dysfunction, senescence, and vascular ageing
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The Event

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ESC Congress 2026

28 August 2026 13:27 CET
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