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Progesterone alleviates vascular endothelial senescence through progesterone receptor isoform b–dependent repression of kelch-like family member 38 and stabilisation of sirtuin 1

28 August 2026 (12:15 - 13:00)
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Congress Presentation Part of: Endothelial biology and vascular function Stem Cells, Cell Cycle, Cell Senescence, Cell Death ESC Professional Premium Access ESC Congress 2026 European Society of Cardiology

About the speaker

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Doctor Dingyi Lyu

The First Affiliated Hospital of Chongqing Medical University, Chongqing (China)

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Transcription factor NFAT1 mediates endothelial-to-mesenchymal transition and atherogenesis under disturbed flow conditions
Doctor J. Chen (Zhuhai, CN)
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Inhibition of miR-148a-3p attenuates endothelial senescence and enhances angiogenesis after myocardial infarction
Miss I. Wolff (Halle, DE)
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The PlGF-NRP1 pathway primes splenic immune response to increase blood pressure
Doctor S. Perrotta (Rome, IT)
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Cellular deep proteomic profiling elucidates NLRP3 inflammasome and immunothrombosis effects of GLP-1 receptor agonist: a controlled intervention study
Assistant Professor Y. Chan (Hong Kong, HK)
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Senescence-associated metabolic shift impedes endothelial angiogenic functions
Doctor F. Ito (Kyoto, JP)
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Access the full session

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Endothelial biology and vascular function

The Event

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ESC Congress 2026

28 August 2026 12:15 CET
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