Back

Targeting MEK signalling with PD0325901 halts aortic dilatation and wall stiffening in a murine model of thoracic aortic aneurysm

29 August 2025 (07:00 - 18:00)
Organised by: Logo
Congress Presentation Part of: Targeting vascular inflammation, remodelling, and haemodynamics in hypertension and aortic aneurysms Atherosclerosis, Cerebrovascular Diseases, Aneurysm, Restenosis ESC Professional Premium Access ESC Congress 2025 European Society of Cardiology

About the speaker

Photo
Doctor Khaled Abdelsattar Kassem Mohammed

Bristol Heart Institute, Bristol (United Kingdom of Great Britain & Northern Ireland)

7 More presentations in this session

Presentation thumbnail
Sirtuin-1 prevents perivascular adipose tissue inflammation via adiponectin/adiponectin receptor-2 axis
Doctor S. Velagapudi (Zurich, CH)
Abstract Slides Video
Presentation thumbnail
Role of heterogeneous nuclear ribonucleoprotein A1 in proteomic remodeling before and after plexiform lesion formation in the Sugen/hypoxia rat model
Doctor Y. Morimoto (Suita, JP)
Abstract Slides Video
Presentation thumbnail
Cannabigerol as a vasodilatory and blood pressure-lowering agent in spontaneously hypertensive rats
Doctor A. Krzyzewska (Bialystok, PL)
Abstract Slides Video
Presentation thumbnail
Rapid prediction of pulsatile hemodynamics in the aortic arch based on physics-informed neural networks
Mr X. Zhang (Beijing, CN)
Abstract Slides Video
Presentation thumbnail
NAT10 promotes aortic aneurysms through lysine acetylation modification
Doctor C. Yu (Fuzhou, CN)
Abstract Slides Video

Access the full session

Session thumbnail
Targeting vascular inflammation, remodelling, and haemodynamics in hypertension and aortic aneurysms

The Event

Event poster

ESC Congress 2025

29 August - 1 September 2025
You may be interested in
thumbnail
Congress Presentation
Exploring adventitial pericyte dysfunction and MEK/ERK signalling as therapeutic targets in thoracic aortic aneurysm
thumbnail
Congress Presentation
Oral low-dose rapamycin treatment prevents aortic aneurysms in marfan mice
thumbnail
Congress Presentation
Exploration of cyclophilin A antibody anti-eCypA as a new approach in the treatment of marfan syndrome

ESC 365 is supported by

novartis Explore sponsored resources

ESC 365 is supported by

novartis Explore sponsored resources