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PI3Ka protects against arteriosclerosis progression and plaque instability by controlling vascular smooth muscle cell functions

31 August 2025 (10:15 - 11:00)
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Congress Presentation Part of: Molecular drivers of vascular remodelling: from atherosclerosis to aneurysm therapy Signal Transduction, Mechanotransduction ESC Professional Premium Access ESC Congress 2025 European Society of Cardiology

About the speaker

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Doctor Mario Zierden

Cologne University Hospital - Heart Center, Cologne (Germany)

7 More presentations in this session

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VasCraft: new decellularized and re-endothelialized human vascular graft produced by tissue engineering for use in arterial bypass
Mrs G. Iraola Picornell (Badalona, Barcelona, ES)
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Dapagliflozin suppresses vascular smooth muscle cell senescence by promoting autophagy
Doctor H. Yang (Changsha, CN)
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Evidence from normal human arteries: IRF7 triggers atherosclerosis by enhancing vascular smooth muscle cells inflammation
Doctor S. Cheng (Nanjing, CN)
Abstract Slides Video
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Mass spectrometry-based proteomics identifies high glucose-induced changes in vascular smooth muscle (VSMCs) and sustained extracellular signal-regulated kinases (ERK) activation
Mrs R. Aldahhasi (Leicester, GB)
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MicroRNA-31-5p promotes vascular remodeling by modulating smooth muscle cell activity via STK40
Doctor K. Kalies (Halle, DE)
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Access the full session

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Molecular drivers of vascular remodelling: from atherosclerosis to aneurysm therapy

The Event

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ESC Congress 2025

31 August 2025 10:15 CET
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ESC 365 is supported by

novartis Explore sponsored resources