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High uric acid induces vascular endothelial cell injury via XBP1-PKM2 mediated glycolytic inhibition

30 August 2024 (08:00 - 17:30)
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Congress Presentation Part of: Targeting endothelial function Vascular Tone, Permeability, Microcirculation ESC Professional Premium Access ESC Congress 2024 European Society of Cardiology

About the speakers

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Doctor Shalaimaiti Shali

Zhongshan Hospital Fudan University, Shanghai (China)

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Professor Yuxiang Dai

Zhongshan Hospital Fudan University, Shanghai (China)

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Increased endothelial cell uptake of erythrocyte-derived extracellular vesicles carrying arginase-1 induces endothelial dysfunction in type 2 diabetes
Doctor A. Collado (Stockholm, SE)
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Blockade of endothelial to mesenchymal transition (EndMT) by an inhibitor of histone methyltransferase EZH2 attenuates atherosclerosis in diabetes
Doctor A. Khan (Melbourne, AU)
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SMAD3 silencing induces Epithelial-to-Mesenchymal Transition (EMT) towards cardiac pericyte progenitors with proangiogenic potential in hiPSC-derived epicardial cells
Doctor Y. Miyoshi (Kyoto, JP)
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Inhibition of ketohexokinase prevents fructose-induced insulin resistance and endothelial dysfunction in high fat and sucrose-fed mice via enhancing energy expenditure
Doctor H. Viswambharan (Leeds, GB)
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Restoration of autophagy reduces diabetes-induced endothelial dysfunction
Doctor L. D'Ambrosio (Venafro, IT)
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Access the full session

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Targeting endothelial function

The Event

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ESC Congress 2024

30 August - 2 September 2024

ESC 365 is supported by

novartis Explore sponsored resources

ESC 365 is supported by

novartis Explore sponsored resources