Characterisation of hypertrophic response and the effect of a GATA4-targeting compound on the phenotype of hypertrophic cardiomyopathy patient-derived hiPSC-cardiomyocytes

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Characterisation of hypertrophic response and the effect of a GATA4-targeting compound on the phenotype of hypertrophic cardiomyopathy patient-derived hiPSC-cardiomyocytes

Session: IPS and other cell models

Topic: Drugs, Drug Targets

Speaker: Ms S. Pohjavaara (Helsinki, FI)

Event: ESC Congress 2023

Congress Presentation

About the speaker

Ms Saana Annika Pohjavaara

University of Helsinki, Helsinki (Finland)

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Sarcomere disassembly and transfection efficiency in proliferating human iPSC-derived cardiomyocytes

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HIF-1 regulates common bidirectional gene expression changes during hypoxia and iron deficiency in human induced pluripotent stem cell derived cardiomyocytes

Speaker: Doctor C. Papadopoulou (Cambridge, GB)

Massive expansion of functional human iPSC-derived cardiomyocytes by concomitant glycogen synthase kinase-3 beta inhibition and removal of cell-cell contact

Speaker: Assistant Professor J. Buikema (Amsterdam, NL)

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Abstract

Slides

Scalable and stable human pluripotent stem cell-derived microvascular-like endothelial cells for cardiac regeneration and disease modelling applications.

Speaker: Doctor Q. Majid (Helsinki, FI)

Development of a human in vitro model of bone marrow vascular niche on a chip to study CD34+ hematopoietic stem/progenitor cells function in diabetes

Speaker: Doctor M. Campanile (Milan, IT)

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IPS and other cell models

Speakers: Ms S. Pohjavaara, Mr Q. Yuan, Doctor C. Papadopoulou, Assistant Professor J. Buikema, Doctor Q. Majid...

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About the event

ESC Congress 2023

25 August - 28 August 2023

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