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PDE1 inhibition and adenosine A2A receptor activation synergistically potentiates spontaneous calcium waves and transients in mouse ventricular myocytes

Session: Mechanisms of ventricular arrhythmias
Topic: Ion Channels, Electrophysiology
Speaker: Mr S. Casabella-Ramon (Barcelona, ES)
Event: ESC Congress 2022

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Mr Sergi Casabella-Ramon

Barcelona (Spain)
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7 more presentations in this session

Synapsin 2 regulates NCX1 trafficking and is down-regulated in the failing myocardium, which increases the risk of ventricular arrhythmia and heart failure mortality

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Empagliflozin attenuates arrhythmogenesis via inhibition of O-GlcNAcylation in diastolic phase of diabetic cardiomyopathy.

Speaker: Doctor T. Kadosaka (Sapporo, JP)

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Disease-associated calmodulin mutations disrupt L-type Ca2+ channel (Cav1.2) activity and CaMKIIdelta phosphorylation in long QT syndrome

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Long QT syndrome-associated calmodulin mutations and their interactions with the Kv7.1 voltage-gated potassium channel

Speaker: Mr L. McCormick (Leeds, GB)

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Utility of in vivo zebrafish cardiac assay to predict the functional impact of KCNQ1 variants

Speaker: Mr S. Cui (Kanazawa, JP)

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Access the full session

Mechanisms of ventricular arrhythmias

Speakers: Mr S. Casabella-Ramon, Doctor A. Ottesen, Doctor T. Kadosaka, Assistant Professor N. Helassa, Mr L. McCormick...
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ESC Congress 2022

26 August - 29 August 2022

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