Hypoxia induces gene-specific epigenetic modifications in human cardiac fibroblasts which are associated with the development of myocardial fibrosis and aberrant post-ischemic cardiac remodelling
Intramyocardial delivery of mesenchymal stem cells transfected with minicircle-HIF-1a decreases LV adverse remodelling via release of cardioprotective miRNAs and pro-angiogenic factors