In the middle of the journey of his life - the straight way was lost*

26 February 2023
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The case

The patient in this clinical case – like Dante Alighieri, the famous Italian poet – had to face certain troubles in the middle of the journey of his life. A 40-year-old male, Caucasian, amateur runner, approached our institute for a preparticipation screening for competitive sports activities. Asymptomatic at rest and during exercise. He had no family history for sudden cardiac death or heart diseases. He reported only hypercholesterolaemia (TC: 220 mg/dL) in familial dyslipidaemia and mild mitral valve prolapse, in regular echocardiographic follow-up.

Clinical examination was normal, resting arterial blood pressure in optimal control (105/65 mmHg).

Resting ECG was normal for athletes, showing sinus rhythm, 59 bpm and an incomplete right bundle branch block (Figure1).

Figure 1: resting ECG

2023-01-Quiz-Figure-1.jpg

The patient was at low risk according to the SCORE2 cardiovascular risk chart (SCORE2 < 2.5%)

He performed a maximal exercise test on a treadmill, RPE 18/20 reaching 90% of age-related maximum heart rate. Figures 2 and 3 show the athlete’s 12-lead ECG at peak exercise and at the second minute of recovery, respectively. The patient was always asymptomatic during exercise and in the recovery period; no major arrhythmias have been registered.

Figure 2: ECG at peak exercise

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Figure 3: ECG at the second minute of recovery

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How would you describe these findings in your medical report, and would you prescribe further second-line investigations, based on which clinical suspicion?

 

 

 

 

 

References

1. Ermolao A, Gasperetti A et Al. Comparison of cardiovascular screening guidelines for middle‐ aged/older adults. Scand J Med Sci Sports. 2019;29:1375–1382.
2. Fletcher GF, Ades PA et Al. Exercise Standards for Testing and Training. A Scientific Statement from the American Heart Association. Circulation. 2013;128:873-934.
3. Guazzi M, Adams V et Al. European Association for Cardiovascular Prevention & Rehabilitation; American Heart Association. EACPR/AHA Scientific Statement. Clinical recommendations for cardiopulmonary exercise testing data assessment in specific patient populations. Circulation. 2012;126(18):2261-74.
4. Belardinelli R, Lacalaprice F et Al. Cardiopulmonary exercise testing is more accurate than ECG-stress testing in diagnosing myocardial ischemia in subjects with chest pain. Int J Cardiol. 2014;174(2):337-42.
5. Ermolao A, Roman F et Al, Coronary CT angiography in asymptomatic middle-aged athletes with ST segment anomalies during maximal exercise test. Scand J Med Sci Sports. 2016;26: 57–63.
6. Finocchiaro G, Behr ER et Al. Anomalous Coronary Artery Origin and Sudden Cardiac Death. Clinical and Pathological Insights from a National Pathology Registry. J Am Coll Cardiol EP. 2019;5:516–22.
7. Gentile F, Castiglione V et Al. Coronary Artery Anomalies. Circulation. 2021;144(12):983-996.
8. Pelliccia A, Sharma S et Al. 2020 ESC Guidelines on sports cardiology and exercise in patients with cardiovascular disease. Eur Heart J. 2020;1-80.

Notes to editor

Author information:

Borasio, Nicola, MD
Quinto, Giulia, MD
Favero, Claudia, MD
Ermolao, Andrea, MD
Neunhaeuserer, Daniel, MD, PhD

Sports and Exercise Medicine Division, Department of Medicine, University of Padova.

Sports and Exercise Medicine Clinical Network of Veneto Region, Italy.

Contributors

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