Italian Association of Hospital Cardiologists Position Paper ‘Gender discrepancy: time to implement gender-based clinical management’
European Heart Journal Supplements
Abstract
It has been well assessed that women have been widely under-represented in cardiovascular clinical trials. Moreover, a significant discrepancy in pharmacological and interventional strategies has been reported. Therefore, poor outcomes and more significant mortality have been shown in many diseases. Pharmacokinetic and pharmacodynamic differences in drug metabolism have also been described so that effectiveness could be different according to sex. However, awareness about the gender gap remains too scarce. Consequently, gender-specific guidelines are lacking, and the need for a sex-specific approach has become more evident in the last few years. This paper aims to evaluate different therapeutic approaches to managing the most common women’s diseases.
Contributors
Michele Massimo Gulizia
Author
Maria Teresa Manes
Author
Maurizio Giuseppe Abrignani
Author
Francesco Antonio Benedetto
Author
Irma Bisceglia
Author
Silvana Brigido
Author
Pasquale Caldarola
Author
Maria Laura Canale
Author
Giorgio Caretta
Author
Roberto Ceravolo
Author
Alaide Chieffo
Author
Cristina Chimenti
Author
Stefano Cornara
Author
Ada Cutolo
Author
Irene Di Matteo
Author
Concetta Di Nora
Author
Francesco Fattirolli
Author
Silvia Favilli
Author
Giuseppina Maura Francese
Author
Sandro Gelsomino
Author
Giovanna Geraci
Author
Simona Giubilato
Author
Nadia Ingianni
Author
Annamaria Iorio
Author
Francesca Lanni
Author
Andrea Montalto
Author
Federico Nardi
Author
Alessandro Navazio
Author
Martina Nesti
Author
Iris Parrini
Author
Annarita Pilleri
Author
Andrea Pozzi
Author
Carmelo Massimiliano Rao
Author
Carmine Riccio
Author
Roberta Rossini
Author
Serafina Valente
Author
Giuseppe Zuccalà
Author
Domenico Gabrielli
Author
Furio Colivicchi
Author
Fabrizio Oliva
Author
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