TRI-SCORE and benefit of intervention in patients with severe tricuspid regurgitation
European Heart Journal
Abstract
Benefit of tricuspid regurgitation (TR) correction and timing of intervention are unclear. This study aimed to compare survival rates after surgical or transcatheter intervention to conservative management according to a TR clinical stage as assessed using the TRI-SCORE.
A total of 2,413 patients with severe isolated functional TR were enrolled in TRIGISTRY (1217 conservatively managed, 551 isolated tricuspid valve surgery, and 645 transcatheter valve repair). The primary endpoint was survival at 2 years.
The TRI-SCORE was low (≤3) in 32%, intermediate (4–5) in 33%, and high (≥6) in 35%. A successful correction was achieved in 97% and 65% of patients in the surgical and transcatheter groups, respectively. Survival rates decreased with the TRI-SCORE in the three treatment groups (all
Survival progressively decreased with the TRI-SCORE irrespective of treatment modality. Compared to conservative management, an early and successful surgical or transcatheter intervention improved 2-year survival in patients at low and, to a lower extent, intermediate TRI-SCORE, while no benefit was observed in the high TRI-SCORE category.
Contributors
Maurizio Taramasso
Author
Giovanni Benfari
Author
Karl-Patrick Kresoja
Author
Fernando Juarez-Casso
Author
Yohann Bohbot
Author
Christos Iliadis
Author
Giulio Russo
Author
Yan Topilsky
Author
Marcel Weber
Author
Luis Nombela-Franco
Author
Alessandra Sala
Author
Andrea Eixerés-Esteve
Author
Bernard Iung
Author
Jean-François Obadia
Author
Rodrigo Estevez Loureiro
Author
Elisabeth Riant
Author
Erwan Donal
Author
Jörg Hausleiter
Author
Luigi Badano
Author
Thierry Le Tourneau
Author
Augustin Coisne
Author
Thomas Modine
Author
Azeem Latib
Author
Stephan Windecker
Author
Jose Luis Zamorano
Author
Ralph Stephan von Bardeleben
Author
Gilbert H L Tang
Author
Rebecca Hahn
Author
John Webb
Author
Denisa Muraru
Author
Mohammed Nejjari
Author
Michele De Bonis
Author
Manuel Carnero-Alcazar
Author
Georg Nickenig
Author
Christophe Tribouilloy
Author
Volker Rudolph
Author
Juan Crestanello
Author
Philipp Lurz
Author
Philipp Bartko
Author
Francesco Maisano
Author
Jeroen Bax
Author
Maurice Enriquez-Sarano
Author
Julien Dreyfus
Author
Xavier Galloo
Author
Maurizio Taramasso
Author
Gregor Heitzinger
Author
Giovanni Benfari
Author
Karl-Patrick Kresoja
Author
Fernando Juarez-Casso
Author
Hazem Omran
Author
Yohan Bohbot
Author
Christos Iliadis
Author
Giulio Russo
Author
Yan Topilsky
Author
Marcel Weber
Author
Luis Nombela-Franco
Author
Alessandra Sala
Author
Andrea Eixerés-Esteve
Author
Bernard Iung
Author
Jean-François Obadia
Author
Rodrigo Estevez Loureiro
Author
Elisabeth Riant
Author
Pascal Lim
Author
Baptiste Bazire
Author
Erwan Donal
Author
Jörg Hausleiter
Author
Luigi Badano
Author
Thierry Le Tourneau
Author
Augustin Coisne
Author
Thomas Modine
Author
Yoan Lavie-Badie
Author
Fabien Doguet
Author
Gilbert Habib
Author
Christine Selton-Suty
Author
Nina Ajmone-Marsan
Author
Azeem Latib
Author
Lukas Stolz
Author
Fabien Praz
Author
Stephan Windecker
Author
Jose Luis Zamorano
Author
Ralph Stephan von Bardeleben
Author
Tobias Ruf
Author
Gilbert H L Tang
Author
Rebecca Hahn
Author
Edith Lubos
Author
John Webb
Author
Joachim Schofer
Author
Neil Fam
Author
Alexander Lauten
Author
Giovanni Pedrazzini
Author
Josep Rodés-Cabau
Author
Denisa Muraru
Author
Mohammed Nejjari
Author
Hector Michelena
Author
Mara Gavazzoni
Author
Jorge Solís
Author
Michele Flagiello
Author
Costin Radu
Author
Yannick Mbaki
Author
Jacques Tomasi
Author
Thomas Senage
Author
Vincent Chan
Author
Kenza Rahmouni
Author
Hannes Alessandrini
Author
Damien Eyharts
Author
Florence Viau
Author
Dominique Himbert
Author
Horst Sievert
Author
Florian Eggenspieler
Author
Martin Nicol
Author
Michele De Bonis
Author
Manuel Carnero-Alcazar
Author
Georg Nickenig
Author
Romain Pfister
Author
Christophe Tribouilloy
Author
Volker Rudolph
Author
Juan Crestanello
Author
Philipp Lurz
Author
Philipp Bartko
Author
Francesco Maisano
Author
Jeroen Bax
Author
Maurice Enriquez-Sarano
Author
David Messika-Zeitoun
Author
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