Perspectives: Rationale and design of the ISACS-TC (International Survey of Acute Coronary Syndromes in Transitional Countries) project
European Heart Journal Supplements

Abstract
During the past 10 years, the health of people in Eastern Europe and the former Soviet Union has undergone changes very different from the health patterns seen in their Western counterparts. Mortality from cardiovascular disease has been decreasing continuously in the USA and many Western European countries, but it has increased or remained unchanged in many of the states of Eastern Europe. Analysis of this phenomenon has been hindered by insufficient information. The International Registry of Acute Coronary Syndromes registry study in Transitional Countries (ISACS-TC) is both a retrospective—over a 1-year period—and prospective study which was designed in order to obtain data of patients with acute coronary syndromes (ACSs) in countries with economy in transition in Central and Eastern Europe, and herewith control and optimize internationally guideline recommended therapies in these countries. Adhesion to the project was given by 112 Collaborating Centres in 17 countries with economy in transition (Albania, Bosnia and Herzegovina, Belarius, Bulgaria, Croatia, Hungary, Kosovo, Latvia, Lithuania, Macedonia, Moldova, Montenegro, Romania, Russian Federation, Serbia, Slovakia, Slovenia, and Ukraine). A total of 47 cluster sites in 11 countries in Central and Eastern Europe are currently collaborating in ISACS-TC. The registry encourages optimal individualization of evidence-based therapies and the international patient body ensures good representation of multiple practice patterns. It may help to make an additional improvement in clinical outcomes of countries with economy in transition.
Contributors

Lina Badimon
Author

Olivia Manfrini
Author

Sergei Boytsov
Author

Knežević Božidarka
Author

Irfan Daullxhiu
Author

Mirza Dilic
Author

Maria Dorobantu
Author

Andreis Erglis
Author

Valery Gafarov
Author

Christopher P. Gale
Author

Eva Goncalvesova
Author

Asen Goudev
Author

Olivja Gustiene
Author

Alistair Hall
Author

Irena Karpova
Author

Sasko Kedev
Author

Nicolay Manak
Author

Davor Miličić
Author

Miograd Ostojic
Author

Alexander N. Parkhomenko
Author

Mihail Popovici
Author

Martin Studenkan
Author

Kalman Toth
Author

Dijana Trninić
Author

Zorana Vasiljevic
Author

Ilja Zakke
Author

Remigijus Zaliunas
Author

Raffaele Bugiardini
Author

Viola Vaccarino
Author

Olivia Manfrini
Author

Lina Badimon
Author

Nicolay Manak
Author

Irena Karpova
Author

Mirza Dilic
Author

Dijana Trninic
Author

Assen Goudev
Author

Davor Milicic
Author

Kalman Toth
Author

Irfan Daullxhiu
Author

Andrejs Erglis
Author

Ilja Zakke
Author

Remigius Zaliunas
Author

Olivija Gustiene
Author

Sasko Kedev
Author

Mihail Popovici
Author

Bozidarka Knezevic
Author

Sergei Boytsov
Author

Valery Gafarov
Author

Maria Dorubantu
Author

Zorana Vasiljevic
Author

Miodrag Ojstoic
Author

Eva Goncalvesova
Author

Martin Studencan
Author

Alexander N Parkhomenko
Author

Alistair Hall
Author

Christopher Gale
Author

Irena Karpova
Author

Nicoly Manak
Author

Milica Lovric
Author

Robert Korać
Author

Dragana Mandic
Author

Vlado Vujović
Author

Milan Blagojević
Author

Jovana Milekić
Author

Elina Trendafilova
Author

Desislava Somleva
Author

Ljiljana Krivokapic
Author

Gordana Rajovic
Author

Omer Šahmanović
Author

Mirko Saranovic
Author

Colovic Radoman
Author

Slavica Cvijovic Tomic
Author

Vujica Ljubic
Author

Milan Velickovic
Author

Sonja Radojicic
Author

Catalina Arsenescu-Georfescu
Author

Smaranda Garbea
Author

Capalneanu Radu
Author

Dan Olinic
Author

Pop Calin
Author

Alexandru Chifor
Author

Katalin Babes
Author

Dan Dominic lonescu
Author

Elvira Craiu
Author

Hie Petrescu
Author

Ionescu Magda
Author

Serban Luminita
Author

Imre Benedek
Author

Sorin Marinescu
Author

Nanea Tiberiu
Author

Gabriela Gheorghe
Author

Ion Malaescu
Author

Nicolae Trocan
Author

Dimulescu Doina
Author

Cezar Macarie
Author

Biljana Putnikovic
Author

Aleksandra Arandjelovic
Author

Natasa Markovic Nikolic
Author

Marija Zdravkovic
Author

Jelena Saric
Author

Slavica Radovanovic
Author

Irena Matic
Author

Nebojsad Srbljak
Author

Goran Davidovic
Author

Stefan Simovic
Author

Sinisa Zivkovic
Author

Slavenka Petkovic-Curic
Author

Martin Studencan
Author

Alexander N Parkhomenko
Author

