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Succinate induces histone succinylation to accelerate arterial calcification by activating FRA1/CREB3L2 axis

30 August 2026 (16:15 - 17:00)
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Congress Presentation Part of: Ageing, senescence, and epigenetic regulation Atherosclerosis, Cerebrovascular Diseases, Aneurysm, Restenosis ESC2026 Premium Access ESC Congress 2026 European Society of Cardiology

About the speaker

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Doctor Zhengyan Guan

the Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen (China)

5 More presentations in this session

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Pharmacological modulation of cardiac senescence reveals divergent transcriptomic reversal patterns in human cardiomyocytes
Doctor K. Megnis (Riga, LV)
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AI-driven prediction and experimental validation of nucleolin phase separation during aging
Professor Y. Li (Suzhou, CN)
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E3 ubiquitin ligase targets nucleolin and modulates its phase separation to suppress ribosome biogenesis in myocardial infarction hearts
Professor Y. Li (Suzhou, CN)
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Targeting PERK-driven proteostasis signalling reveals spermidine-dependent stress resilience in the ageing heart
Ms N. Kanduri (SE)
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Oxidative dysregulation as central mechanisms of PANDA lncRNA in diabetic vasculature
Ms A. Mongelli (Schlieren, CH)
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Ageing, senescence, and epigenetic regulation

The Event

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ESC Congress 2026

30 August 2026 16:15 CET
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