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Succinate links metabolism to atrial fibrillation via multiple mechanisms: the SUCNR1/PKA/ THRα/IP3R1 axis governs calcium dysregulation, electrophysiological remodeling, and inflammatory activation

28 August 2026 (15:15 - 16:00)
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Congress Presentation Part of: Arrhythmias, atrial biology, and electrophysiology Arrhythmias ESC2026 Premium Access ESC Congress 2026 European Society of Cardiology

About the speaker

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Doctor Yaping Wang

The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou (China)

7 More presentations in this session

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Direct acute arrhythmic and negative inotropic effects of ibrutinib, but not doxorubicin, in human atrial myocardium
Mr Y. Berger (Berlin, DE)
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Effects of SGLT2 inhibitors on the atrial rhythm: Sotagliflozin modifies the activity of NaV1.5
Mr M. Stelzle (Heidelberg, DE)
Abstract Slides Video
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Modulation of cytoplasmic polyadenylation element binding protein 3 changes electrophysiological features and calcium handling in cardiomyocytes
Mr C. Yang (Mannheim, DE)
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Electrophysiological basis and pharmacological responses in short QT syndrome type 5: insights from iPSC-derived cardiomyocytes
Doctor Z. Xue (Mannheim, DE)
Abstract Slides Video
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Sympathetic activation of L-type Ca2+ current and Na+/Ca2+ exchange current in canine ventricular cardiomyocytes
Doctor B. Horvath (Debrecen, HU)
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Access the full session

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Arrhythmias, atrial biology, and electrophysiology

The Event

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ESC Congress 2026

28 August 2026 15:15 CET
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