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ECM-derived exerkines COL1A2-pep1 attenuate cardiac remodeling by enhancing mitophagy through the mtDNA-cGAS-STING pathway

30 August 2026 (12:15 - 13:00)
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Congress Presentation Part of: Cardiac hypertrophy and pressure overload Fibrosis ESC2026 Premium Access ESC Congress 2026 European Society of Cardiology

About the speakers

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Doctor Ling-Hong Shen

Shanghai Chest Hospital, Shanghai (China)

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Mr Hongfei Ci

Shanghai Chest Hospital, Shanghai (China)

6 More presentations in this session

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Endothelial redox signalling safeguards metabolic and transcriptional integrity and blocks middle-age cardiac hypertrophy
Ms M. Drekolia (Heidelberg, DE)
Abstract Slides
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Ketone bodies independently of metabolic pathway attenuate cardiac hypertrophy through β-hydroxybutyrylation
Doctor J. Du (Chengdu, CN)
Abstract Slides
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Sestrin2 protects against pressure overload–induced pathological cardiac hypertrophy via ULK1
Mr T. Liu (CN)
Abstract Slides
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The Role of Neuropeptide Y in Human Cardiac Hypertrophy after Myocardial Infarction
Miss L. Ganzer (GB)
Abstract Slides
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A porcine model of pressure overload–induced cardiac hypertrophy via catheter-based aortic stent implantation for aav-mediated gene therapy studies
Ms M. Corsten (Munich, DE)

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Cardiac hypertrophy and pressure overload

The Event

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ESC Congress 2026

30 August 2026 12:15 CET
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