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Targeting fibroblast CTHRC1 ameliorates cardiac fibrosis and dysfunction by suppressing cardiomyocyte NLRP3 inflammasome activation

29 August 2026 (12:15 - 13:00)
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Congress Presentation Part of: Heart failure: a multidimensional approach Ventricular Remodelling ESC2026 Premium Access ESC Congress 2026 European Society of Cardiology

About the speaker

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Doctor Xiaoqing Wang

Sichuan Provincial People's Hospital, Chengdu (China)

5 More presentations in this session

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Low-normal systolic blood pressure in heart failure: hemodynamic frailty in HFrEF, J-Curve phenotype in HFpEF/HFmrEF, and the prognostic role of in-hospital SBP drops—A targeted evidence synthesis
Doctor F. Veneziano (Groningen, NL)
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Integrated multi-omics analysis reveals the molecular mechanisms of renal denervation in alleviating diabetic cardiomyopathy
Mr F. Zhang (Tianjin, CN) Doctor Z. Li (Tianjin, CN)
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Macrophage-driven NLRP3 inflammasome activation impairs cardiomyocyte function in HFpEF
Ms C. Dong (Bochum, DE)
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Temporal cardiomyocyte-specific TRF2 loss drives TERRA activation and systolic heart failure
Ms S. Khraisat (Mainz, DE)
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Integrated molecular profiling of preclinical and clinical cardiac xenotransplants
Doctor N. Hadizadeh (Munich, DE)
Abstract Slides

Access the full session

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Heart failure: a multidimensional approach

The Event

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ESC Congress 2026

29 August 2026 12:15 CET
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