Back

Attenuation of medial arterial calcification by senescent vascular smooth muscle cell clearance: a uPAR-targeted senolytic therapy

29 August 2026 (14:15 - 15:00)
Organised by: Logo
Congress Presentation Part of: Mechanistic insights into aortic diseases Pharmacotherapy ESC Professional Premium Access ESC Congress 2026 European Society of Cardiology

About the speaker

Photo
Miss Mingxuan Zhang

The Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen (China)

6 More presentations in this session

Presentation thumbnail
Hyperuricemia activates the TLR2–MAPK signaling axis in vascular macrophages to drive aortic dissection
Mr B. Zheng (Shenzhen, CN)
Abstract Slides Video
Presentation thumbnail
Beyond chronological age: identifying accelerated aortic aging through laboratory indicators and geometric phenotyping
Doctor X. Duan (Kunming, CN)
Abstract Slides Video
Presentation thumbnail
Pharmacological inhibition of microplastic uptake prevents endothelial injury
Doctor G. Tortorella (Naples, IT)
Abstract Slides Video
Presentation thumbnail
Pyruvate dehydrogenase kinase 4 Triggers VSMCs phenotype switching and aortic aneurysm/dissection by regulating NLRP3 lactylation
Associate Professor D. Yang (Shanghai, CN)
Abstract Slides Video
Presentation thumbnail
GPR18 plays an atheroprotective role by regulating humoral and effector T-cell responses
Mrs A. Prabhu (Munich, DE)
Abstract Slides Video

Access the full session

Session thumbnail
Mechanistic insights into aortic diseases

The Event

Event poster

ESC Congress 2026

29 August 2026 14:15 CET
You may be interested in
thumbnail
Congress Presentation
Venetoclax attenuates vascular calcification through combined senolytic activity and SOX9/LH3-mediated ECM remodeling
28 August 2026
thumbnail
Congress Presentation
Magnetic particle imaging of macrophage phagocytosis evaluates plaque vulnerability and therapeutic efficacy in atherosclerosis
29 August 2026
thumbnail
Congress Presentation
The role of cellular senescence in aortic dissection
27 August 2023
thumbnail
Congress Presentation
Long non-coding RNA MIAT and MEG3 are crucial regulators of inflammation and calcification in aortic valve stenosis
31 August 2026

ESC 365 is supported by

novartis Explore sponsored resources
novo-nordisk Explore sponsored resources

ESC 365 is supported by

novartis Explore sponsored resources
novo-nordisk Explore sponsored resources