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Single-cell CRISPR perturbation in human adipocytes reveals an omnigenic core remodeling network linking CAD loci to cardiometabolic risk

28 August 2026 (14:30 - 14:42)
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Congress Presentation Part of: Multi-omics and single-cell approaches to assess cardiometabolic risk Genetics, Epigenetics, ncRNA ESC2026 Premium Access ESC Congress 2026 European Society of Cardiology

About the speaker

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Mr Sebastian Jean Doetsch

German Heart Center Muenchen Technical University of Munich, Munich (Germany)

4 More presentations in this session

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Multi-omic dissection of enhancer, transcription factor and ncRNA regulation of epicardial EMT in cardiac development
Doctor J. Nunes Vieira (London, GB)
Abstract Slides Video
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Single-cell and extracellular vesicle profiling reveals fibroblast-macrophage crosstalk in epicardial adipose tissue during acute myocardial infarction
Doctor L. Zhao (Beijing, CN)
Abstract Slides Video
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In vivo single-cell CRISPR screening reveals that Slc7a8 is a key molecule in post-myocardial infarction repair
Doctor S. Huang (Shanghai, CN)
Abstract Slides Video
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Region-specific cellular ecosystems govern divergent remodelling trajectories in hypertrophic cardiomyopathy
Doctor Y. Tan (Shanghai, CN)
Abstract Slides Video

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Multi-omics and single-cell approaches to assess cardiometabolic risk
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The Event

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ESC Congress 2026

28 August 2026 14:30 CET
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