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Preclinical proof of concept for STX-1200: potent LPA editing and Apo(a) knockdown via CasX-based gene editing

1 September 2025 (11:15 - 12:00)
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Congress Presentation Part of: Molecular networks and emerging therapeutics in cardiac pathophysiology Gene Therapy, Cell Therapy ESC Professional Premium Access ESC Congress 2025 European Society of Cardiology

About the speaker

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Doctor Aarif Khakoo

(United States of America)

6 More presentations in this session

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Early life stress Induces age-dependent cardiac dysfunction in exposed parents and in their offspring
Doctor S. Mohammed (Zurich, CH)
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mRNA therapeutics encoding multiple cardiac-reparative factors using polyplex nanomicelle attenuating myocardial infarction
Doctor K. Handa (Suita, JP)
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miR-125b-5p and miR-125b-1-3p mediate TGF-beta response in ischemic heart failure
Mr I. Hagerstrom (Helsingfors, FI)
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Therapeutic potential of pxl065 (deuterium-stabilized r-enantiomer of pioglitazone) in hypertrophic cardiomyopathy
Ms A. Pfaller (Munich, DE)
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Prime editing correction of an Nkx2-5 variant in a murine congenital heart disease model
Mr D. Nishijo (Tokyo, JP)
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Access the full session

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Molecular networks and emerging therapeutics in cardiac pathophysiology

The Event

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ESC Congress 2025

1 September 2025 11:15 CET
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ESC 365 is supported by

novartis Explore sponsored resources
novo-nordisk Explore sponsored resources