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Prevention of aortic valve stenosis through modulation of LXRb using saringosterol

31 August 2025 (12:15 - 13:00)
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Congress Presentation Part of: Molecular mechanisms and therapeutic targets in aortic valve disease and calcification Valvular Heart Disease ESC Professional Premium Access ESC Congress 2025 European Society of Cardiology

About the speaker

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Doctor Moritz Noethel

Heartcenter Bonn, University Hospital Bonn, Bonn (Germany)

6 More presentations in this session

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The K+ channel KCa3.1 promotes contraction in aortic stenosis valve myofibroblast cells
Miss M. Whitfield (Leicester, GB)
Abstract Slides
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Novel ex-vivo calcification model for human aortic valves reveals patient-specific effect of compound.
Ms M. El Ouraoui (Leiden, NL)
Abstract Slides Video
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Glycolysis blockade reduces synthesis and maturation of glycoproteins as well as leukocyte adhesion in inflamed aortic valve cells
Miss M. Peral-Rodrigo (Valladolid, ES)
Abstract Slides Video
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Activation of cGMP-PKG signaling pathway attenuates aortic valve calcification through ULK1-mediated autophagy
Doctor Y. Wang (Chengdu, CN)
Abstract Slides Video
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Targeted modulation of sphingolipid signaling to inhibit the progression of aortic valve disease
Doctor M. Benkhoff (Duesseldorf, DE)
Abstract Slides Video

Access the full session

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Molecular mechanisms and therapeutic targets in aortic valve disease and calcification

The Event

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ESC Congress 2025

31 August 2025 12:15 CET
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ESC 365 is supported by

novartis Explore sponsored resources