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Targeting BRD4-HK2 reverses the meta-inflammatory shift in perivascular adipose tissue and rescues cardiometabolic vascular dysfunction.

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About the speaker

Assistant Professor Alessandro Mengozzi

University of Pisa, Pisa (Italy)
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5 more presentations in this session

Targeting the histone methyltransferase SETD7 rescues diabetes-induced impairment of angiogenic response by transcriptional repression of semaphorin 3G

Speaker: Doctor S. Mohammed (Zurich, CH)

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Chromatin remodeling by the histone methyltransferase SETD2 drives cardiometabolic heart failure with preserved ejection fraction

Speaker: Doctor S. Costantino (Zurich, CH)

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Epigenetic BET inhibitor apabetalone counters inflammatory and fibrotic processes in activated cardiac fibroblasts providing insight into reduced hospitalizations for heart failure in BETonMACE trial

Speaker: Doctor E. Kulikowski (Calgary, CA)

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The BET inhibitor Apabetalone protects against heart failure with preserved ejection fraction by suppressing myocardial inflammation

Speaker: Doctor E. Gorica (Zurich, CH)

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RBM20 promotes doxorubicin-induced cardiotoxicity by Atp6v0a1 alternative splicing

Speaker: Doctor Z. Qiu (Shanghai, CN)

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Access the full session

Epigenetic targets in cardiovascular disease

Speakers: Assistant Professor A. Mengozzi, Doctor S. Mohammed, Doctor S. Costantino, Doctor E. Kulikowski, Doctor E. Gorica...
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ESC Congress 2024

30 August - 2 September 2024

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