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A novel murine model of stress-induced cardiomyopathy achieved by chemogenetic stimulation of the locus coeruleus-norepinephrine system

30 August 2024 (08:00 - 17:30)
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Congress Presentation Part of: Novel mechanisms in arrhythmogenic cardiac diseases Cardiomyopathies ESC Professional Premium Access ESC Congress 2024 European Society of Cardiology

About the speaker

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Doctor Stefano Ministrini

University of Zurich, Zurich (Switzerland)

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Reduced Na current in dystrophin-deficient ventricular cardiomyocytes is rescued by tenascin-C inhibition
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MRPL44 haploinsufficient mouse spontaneously develops hypertrophic cardiomyopathy and shows systolic dysfunction after aldosterone treatment
Professor R. Okamoto (Tsu, JP)
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Phosphoproteomics of PLN R14del heart tissue reveals major myocyte degenerate phenotype, and is attenuated by PLN antisense treatment in vitro
Mr F. Deiman (Groningen, NL)
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Burst-like transcription of MYH7, allelic and contractile imbalance already in early stage hiPSC-cardiomyocytes indicate these as pathogenic factors in Hypertrophic Cardiomyopathy
Doctor T. Kraft (Hannover, DE)
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Novel mechanisms in arrhythmogenic cardiac diseases
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The Event

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ESC Congress 2024

30 August - 2 September 2024
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