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SGK1 inhibition normalizes action potential duration in transgenic LQT2 rabbits but not in LQT1, suggesting a novel gene-specific therapeutic approach in long QT syndrome

12 April 2024 (08:30 - 14:00)
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Congress Presentation Part of: Inherited arrhythmias: novel mechanisms and therapeutic targets Ion Channels, Electrophysiology CBS PREMIUM ACCESS Frontiers in CardioVascular Biomedicine 2024 Council on Basic Cardiovascular Science

About the speaker

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Miss Miriam Barbieri

University of Bern, Bern (Switzerland)

4 More presentations in this session

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Ventricular hyperinnervation in a mouse model of catecholaminergic polymorphic ventricular tachycardia
Doctor M. O'Reilly (Amsterdam, NL)
Abstract
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Bradycardia in a long QT type 2 family: coinciding KCNH2 and HCN4 variants
Ms J. Copier (Amsterdam, NL)
Abstract
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Maturing hiPSC-cardiomyocytes in cardiac microtissues for accurate preclinical in vitro modelling of long-QT syndrome type 1
Doctor G. Campostrini (Leiden, NL)
Abstract
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Interplay of electrical and mechanical properties in transgenic rabbit models of long-QT and short-QT syndrome
Mr N. Alerni (Bern, CH)
Abstract

Access the full session

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Inherited arrhythmias: novel mechanisms and therapeutic targets

The Event

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Frontiers in CardioVascular Biomedicine 2024

12 April - 14 April 2024

ESC 365 is supported by

novartis Explore sponsored resources

ESC 365 is supported by

novartis Explore sponsored resources