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Dapagliflozin downregulates G protein-coupled receptor Kinase-2 and upregulates regulator of g protein signaling-4 in adrenals to exert sympatholysis in heart failure

25 August 2023 (07:30 - 18:30)
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Congress Presentation Part of: Therapeutic strategies to combat vascular disease Drugs, Drug Targets ESC Professional Premium Access ESC Congress 2023 European Society of Cardiology

About the speaker

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Associate Professor Anastasios Lymperopoulos

Nova Southeastern University, Fort Lauderdale (United States of America)

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Atheroprotective CD40-TRAF6 inhibitors: translational pipeline towards a clinical application
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Characterization of AT-02, a pan-amyloid-binding peptide fusion immunoglobulin with high binding potency, complement activation, and immune cell stimulation
Professor J. Wall (Knoxville, US)
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Effective cardiac mRNA delivery using lipid nanoparticles
Ms M. Labonia (Utrecht, NL)
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HS135, a novel activin and GDF trap, is highly efficacious in preclinical models of pulmonary hypertension and obesity-associated heart failure with preserved ejection fraction
Doctor J. Schoelermann (Montreal, CA)
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Dapagliflozin decreases atherosclerotic plaque instability via regulating macrophage pyroptosis
Doctor L. Xu (Shanghai, CN)
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Access the full session

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Therapeutic strategies to combat vascular disease

The Event

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ESC Congress 2023

25 August - 28 August 2023

ESC 365 is supported by

novartis Explore sponsored resources

ESC 365 is supported by

novartis Explore sponsored resources