Reversal of apixaban and rivaroxaban anticoagulation by andexanet alfa in ANNEXA-A&R as assessed by non-tissue factor (TF)-initiated thrombin generation independent of TF pathway inhibitor (TFPI)
JNJ-9375, a novel exosite 1 thrombin inhibitor does not increase bleeding in a spontaneous gastrointestinal (GI) bleeding model in mice with a mutation of the Adenomatous polyposis coli (Apc) gene