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The platelet protease-activated receptor-4 antagonist, UDM-002555, alone and in combination with aspirin inhibits arterial thrombosis with limited impact on hemostasis in cynomolgus monkeys

27 August 2016 (00:00 - 00:00)
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Congress Presentation Part of: Mechanisms of platelet activation Thrombosis and platelets ESC Premium Access ESC Congress 2016

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Doctor Pancras Wong

Bristol Myers Squibb, Princeton (United States of America)

6 More presentations in this session

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Platelet responsiveness to PAR4 activation in a healthy population and its inhibition by a potent and selective PAR4 antagonist
Doctor K. Downes (Cambridge, GB)
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Can off-pump coronary artery bypass graft surgery be performed 3 days after clopidogrel discontinuation without increasing the bleeding risk in acute coronary syndrome patients?
Mr W. Liu (Beijing, CN)
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Evaluation of immature platelet parameters as compared to established predictors of platelet reactivity after thienopyridine loading
Doctor C. Stratz (Bad Krozingen, DE)
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Impact of diabetes mellitus on the pharmacodynamic effects of ticagrelor versus clopidogrel in troponin-negative acute coronary syndrome patients undergoing ad-hoc percutaneous coronary intervention
Professor J. Sweeny (New York City, US)
Abstract Slides
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Large mean platelet volume is associated with impaired clopidogrel-responsiveness in acute coronary syndrome patients, with no impact on prasugrel or ticagrelor effects
Doctor A. Marcano Fernandez (L'hospitalet De Llobregat, ES)
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Mechanisms of platelet activation

The Event

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ESC Congress 2016

27 August - 31 August 2016

ESC 365 is supported by

novartis Explore sponsored resources

ESC 365 is supported by

novartis Explore sponsored resources