ESC 365 - Doctor Walaa Fakih

Speaker illustration

Doctor Walaa Fakih

INSERM, University of Strasbourg, CRBS, Strasbourg (France)

Member of:

Human epicardial adipose tissue-derived factors promote atrial endothelial dysfunction: role of pro-inflammatory cytokines and AT1R/NADPH oxidases/SGLT2 pro-oxidant pathway

Event: ESC Congress 2024

Topic: Drugs, Drug Targets

Session: Antidiabetic drugs for treatment of cardiovascular disease

TNF-alfa promotes NF-kB-dependent oxidative stress in human left appendages and in atrial endothelial cells: Role of SGLT2

Event: Heart Failure 2024

Topic: Drugs, Drug Targets

Session: Basic science - cardiac disease 3

Increased pro-remodeling and pro-thrombotic responses in the left compared to the right atrial appendage: role of low-grade inflammation and the AT1R/NADPH oxidases/SGLT2 pro-oxidant pathway

Event: ESC Congress 2023

Topic: Drugs, Drug Targets

Session: Myocardial remodelling (3)

Upregulation of SGLT1 and 2 promotes oxidative stress in right atrial appendages of patients with low-grade inflammatory responses: potential role in atrial fibrillation

Event: ESC Congress 2022

Topic: Drugs, Drug Targets

Session: Cellular effectiveness of drug therapies

FXa promotes endothelial dysfunction and pro-remodeling responses in atrial endothelial cells involving PAR1 and 2 and AT1R/NADPH oxidase/SGLT1/2 pro-oxidant pathways

Event: Heart Failure 2022

Topic: Drugs, Drug Targets

Session: New therapeutic approaches for heart failure

Thrombin and factor Xa promote premature senescence and remodeling in areas at risk of the left appendage and in atrial endothelial cells: Potential modulation by SGLT1 and/or SGLT2 inhibition

Event: ESC Congress 2021 - The Digital Experience

Topic: Drugs, Drug Targets

Session: Basic science e-posters

ESC 365 is supported by

Explore sponsored resources

Explore sponsored resources