Dr. deFilippi joined the Inova Heart and Vascular Institute as the Vice-Chair of Academic Affairs in 2016. Previously he was an Associate Professor of Medicine at the University of Maryland. He also serves as the Inova site Principal Investigator for the NIH funded Clinical and Translational Science Awards (CTSA) Program with University of Virginia and Virginia Tech. In his oversight of clinical research he has built IHVI to be a national leader in site based research. Under his mentorship in 2020 two junior IHVI attending received NHLBI K23 award and another received an R01. He serves on the Editorial boards of Circulation, JACC and JACC:Heart Failure. He is an Associate Editor for the Journal of Applied Laboratory Medicine. His research is focused on evaluating in-vitro diagnostics and proteomics discovery for diagnosis, prognosis, and therapy guidance across the spectrum of health from detection of preclinical cardiovascular disease to diagnosis and treatment in the critically ill.