VU University Medical Center, Institute for Cardiovascular Research (ICaRVU) , Amsterdam (Netherlands (The))
Jolanda van der Velden, PhD, is chair of the Department for Physiology at the Amsterdam University Medical Center, and director of the Amsterdam Cardiovascular Sciences Institute. Since 2012 van der Velden is professor of the Netherlands Heart Institute. The main research interest of the van der Velden group is to study the role of sarcomere proteins in cardiac performance for which specific protein analyses and functional assays have been designed. As mutations in sarcomere proteins are a frequent cause of heart disease at young age, research on this topic was initiated with funding from European and prestigious national grants. The national research consotium (DOSIS) funded by the Netherlands Heart Foundation aims to study effects of genetic and environmental modifiers in cardiomyopathy. Studies on the genetic heart disease include basic cell and tissue analyses, which are combined with in vivo cardiovascular imaging in mouse models and human patients.