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Doctor Karoline Bjarnesdatter Rypdal

Center For Clinical Heart Research, Oslo (Norway)
Membership: ESC Professional Member
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Biography
Rypdal is a postdoctoral researcher in the lab of Dr. Ida G. Lunde at Akershus University Hospital and the University of Oslo, with a PhD in basic and translational cardiac research. Our research area is molecular mechanisms of heart failure, with particular focus on fibrosis and the role of extracellular matrix proteins in the heart.
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The collagen-binding proteoglycan fibromodulin is substantially upregulated in the myocardial infarct and affects cardiac function and remodelling in mice
Presentation
The collagen-binding proteoglycan fibromodulin is substantially upregulated in the myocardial infarct and affects cardiac function and remodelling in mice
Deletion of the extracellular matrix glycoprotein ADAMTSL3 increases pro-fibrotic signalling and exacerbates heart failure in mice
Presentation
Deletion of the extracellular matrix glycoprotein ADAMTSL3 increases pro-fibrotic signalling and exacerbates heart failure in mice
Deletion of the matrix glycoprotein ADAMTSL3 results in dilated cardiomyopathy in aortic banded mice
Presentation
Deletion of the matrix glycoprotein ADAMTSL3 results in dilated cardiomyopathy in aortic banded mice
The secreted matrix glycoprotein ADAMTSL3 is up-regulated in heart failure and mediates anti-fibrotic effects in cardiac fibroblasts
Presentation
The secreted matrix glycoprotein ADAMTSL3 is up-regulated in heart failure and mediates anti-fibrotic effects in cardiac fibroblasts

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