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Doctor Pierre-Louis Tharaux

National Institute of Health and Medical Research (INSERM home), Paris (France)
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Biography
Pierre-Louis Tharaux is Research Professor at INSERM, The Paris Cardiovascular Centre – PARCC Division of Nephrology, Georges Pompidou European Hospital, AP-HP, Paris. He is an elected member of the INSERM Scientific Committee on Physiology and Pathophysiology (CSS3)(2016-2020). He is a councilor of the French Society of Cardiology/GRRC (2013-present) and of the French Society of Hypertension (2017-present) and the French Federation of Cardiology (FFC) (2017-present) and acted as a member of the Scientific Program Committee for several international congresses. Research in his laboratory involves analysis of mouse vascular and renal pathophysiology with translation to clinical studies. His work covers: 1- GPCRs and RTK signaling, multi-omic integration in kidney and vascular cells in accelerated ageing, hypertension, diabetes and auto-immune vasculitides. 2- Involvement of innate immunity and endothelial cells in Sickle Cell Nephropathy and Vasculopathy.
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BMP9 is a key player in endothelial identity and its loss is sufficient to induce arteriovenous malformations
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BMP9 is a key player in endothelial identity and its loss is sufficient to induce arteriovenous malformations
19 March 2024