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Professor Atsushi Kuno

Sapporo Medical University, Sapporo (Japan)
Membership: ESC Professional Member
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SIRT1 protects the heart against doxorubicin-induced cardiotoxicity by mediating the DNA damage response via deacetylation of histone H2AX.
Presentation
SIRT1 protects the heart against doxorubicin-induced cardiotoxicity by mediating the DNA damage response via deacetylation of histone H2AX.
The histone deacetylase SIRT1 mediates the proper DNA repair response by targeting histone H2AX to protect against doxorubicin-induced cardiotoxicity.
Presentation
The histone deacetylase SIRT1 mediates the proper DNA repair response by targeting histone H2AX to protect against doxorubicin-induced cardiotoxicity.
The SIRT1 activator resveratrol ameliorates dystrophic cardiomyopathy by promoting mitophagy.
Presentation
The SIRT1 activator resveratrol ameliorates dystrophic cardiomyopathy by promoting mitophagy.
Deletion of SIRT1 in the cardiomyocyte worsens doxorubicin-induced cardiac dysfunction in mice.
Presentation
Deletion of SIRT1 in the cardiomyocyte worsens doxorubicin-induced cardiac dysfunction in mice.

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