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Doctor Gary D Lopaschuk

University of Alberta, Edmonton (Canada)

Dr. Gary D. Lopaschuk is a Distinguished University Professor of Pediatrics at the University of Alberta, Edmonton. His research focuses on the regulation of fatty acid oxidation in the heart, and the mechanism by which high rates of fatty acid oxidation contribute to heart disease and heart failure. He is also examining how alterations in fatty acid metabolism contribute to cardiovascular disease in the diabetic. At a molecular level he has characterized a number of key enzymes important in the regulation of cardiac fatty acid oxidation. He is also developing a number of therapeutic strategies that involve optimizing energy metabolism in the heart that can be used to prevent the development of heart disease, and that can also be used to treat heart failure. His research has resulted in the publication of over 440 original research articles, and is a member of 14 journal editorial boards.

Cardiac energy metabolism in heart failure.

Event: Heart Failure 2022

Topic: Signal Transduction, Mechanotransduction

Session: What fuels the heart matters

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sGLTII inhibitors for heart failure .

Event: ESC CONGRESS 2019

Topic: Drugs, Drug Targets

Session: Success stories in translation from bench to bedside

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Substrate metabolism in diabetes and heart failure.

Event: Heart Failure 2017 - 4th World Congress on Acute Heart Failure

Topic: Metabolism / Diabetes mellitus

Session: Diabetes, obesity and the heart

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Insulin glargine decreases the reliance of the heart on fatty acid oxidation and improves db/db mouse heart function

Event: ESC CONGRESS 2016

Topic: Metabolism and metabolic syndromes

Session: Basic and Translational Science Hot Line II

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