Professor Sharp qualified from Edinburgh Medical School in 1998. He conducted his early training at the Royal Infirmary of Edinburgh, before moving to London for his senior clinical training, completing the Milan-Imperial Interventional Cardiology fellowship under the tutelage of Professor Antonio Colombo. Prof Sharp was awarded an MD postgraduate research degree from the University of Edinburgh for his work on the hypertensive heart and his current research interests include device-based treatments for hypertension, catheter-directed treatments for pulmonary embolism, intracoronary imaging and coronary physiology. He is also a TAVI operator and runs the Cardiff TEER programme.