Doctor.He devotes himself to being a specialized cardiologist. His study mainly focused on communication of cellular organelles such as mitochondria, lysosomes, and the endoplasmic reticulum in cardiomyocytes. The interaction of these ogranelles is invovled in mutiple cell biological progress, in which autophagy receives much interest from Doctor.He. He try to investigate the interaction of these organells and autophagic flux in different cardiovascular diseases and explore the potential cures for them.