Paris Cardiovascular Research Center (PARCC), Paris (France)
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Named lecture - Guido Tarone: In vitro RASopathy model recapitulates the hypertrophic cardiomyopathy pathology and reveals a positive response to mavacamten
Presentation
PAK3 overexpression during stress-induced cardiac hypertrophy dysregulates autophagy augmenting acute cell death and accelerating the development of systolic dysfunction