Staged visceral revascularization prior to central aortic repair in acute type A aortic dissection complicated by mesenteric malperfusion: a case report

European Heart Journal - Case Reports

19 September 2026
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ESC Journals CORONARY ARTERY DISEASE, ACUTE CORONARY SYNDROMES, ACUTE CARDIAC CARE Acute Cardiac Care DISEASES OF THE AORTA, PERIPHERAL VASCULAR DISEASE, STROKE Diseases of the Aorta Cardiovascular Surgery

Abstract

AbstractBackground

Acute type A aortic dissection (ATAAD) complicated by mesenteric malperfusion is among the most lethal cardiovascular emergencies, combining the immediate threat of aortic rupture with rapidly progressive visceral ischaemia. The optimal sequence of intervention remains controversial. Although current guidelines recommend immediate central aortic repair, this strategy may carry particularly high perioperative risk when advanced mesenteric ischaemia is already present.

Case summary

A 54-year-old woman with no relevant medical history presented with ATAAD extending from the sinotubular junction to the iliac bifurcation, complicated by severe mesenteric malperfusion and haemodynamic instability. Following urgent multidisciplinary discussion, a staged strategy was adopted. On Day 0, visceral reperfusion was achieved by iliac-to-superior mesenteric artery bypass with concomitant exploratory laparotomy, combined with thoracic endovascular aortic repair. Progressive intestinal ischaemia over the next 48 h required multiple abdominal surgeries, including right colectomy, left colectomy with ileosigmoidostomy, and cholecystectomy, until bowel viability was controlled. Definitive total aortic arch replacement using a Thoraflex hybrid prosthesis was then performed on Day 6 under cardiopulmonary bypass with brief circulatory arrest. Despite a prolonged and complex postoperative course, the patient survived to hospital discharge.

Discussion

This case illustrates the multidisciplinary decision-making involved in the management of a highly selected patient with ATAAD and established severe mesenteric malperfusion syndrome, in whom the immediate risk of visceral ischaemia was weighed against the substantial risk of delaying central repair.