Incidence and burden of cardiovascular disease attributable to extreme heat in China
European Journal of Preventive Cardiology

Abstract
The increasing frequency of heat events driven by climate change poses a serious challenge to cardiovascular health. This study aimed to investigate the relationship between high temperature and acute cardiovascular disease (CVD) incidence in China and to quantify the heat-related burden of CVD.
A total of 856 357 incident acute CVD cases were used from CVD surveillance in China in 2023. A distributed lag non-linear model was applied to evaluate the dose–response relationship between temperature and CVD incidence, as well as the best linear unbiased prediction of the minimum incidence temperature (MIT). The heat-related burden was quantified using attributable fraction and attributable number for two temperature ranges: all heat and extreme heat. Higher temperatures were associated with an increased risk of acute CVD incidence. Extreme heat exposure resulted in a cumulative relative risk (RR) of 1.17 [95% confidence interval (CI) 1.05–1.30], with the highest cumulative risk observed on the fourth day following exposure. All heat exposure accounted for 3.19% of CVD cases, while extreme heat contributed to 0.08%. The burden was particularly pronounced among individuals aged ≥65 years (RR = 1.20, 95% CI 1.05–1.37), rural populations (RR = 1.18, 95% CI 1.01–1.37), and those living in temperate monsoon and temperate continental climates (RR = 1.25, 95% CI 1.05–1.49). Minimum incidence temperature varied geographically, ranging from 16.0°C in northern regions to 26.2°C in southern regions, with the highest MITs concentrated in tropical areas.
These findings emphasize the urgent need for region-specific public health strategies that integrate climate change adaptation and CVD prevention to mitigate the growing health risks associated with rising temperatures.
Contributors

Xuyan Pei
Author

Haosu Tang
Author

Congyi Zheng
Author

Yue Zhang
Author

Muyi Sun
Author

Qinglan Jia
Author

Siyu Liu
Author

Xin Wang
Author

Ye Tian
Author

Xue Cao
Author

Yixin Tian
Author

Xue Yu
Author

Nuerguli Tuerdi
Author

Chenye Chang
Author

Yujie Zhang
Author

Fan Li
Author

Jialu Yang
Author

Zengwu Wang
Author
State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular D Beijing , China
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