Early patient-reported outcomes and quality of life improvements after PVI. A single center survey

Pulmonary vein isolation (PVI) is the cornerstone rhythm control therapy for atrial fibrillation (AF) management, offering better rhythm control and symptoms relief. While peri-procedural efficacy is well documented, early patient-reported outcomes (PROs) and quality of life remain under-characterized. Understanding patients’ subjective experiences may inform post-procedural care and expectation management.

To evaluate self-reported health status, functional recovery, and overall satisfaction in the early period (30–60 days) following PVI in patients with AF.

A single center, cross-sectional survey was conducted in 100 consecutive patients (aged 30–70 years, both sexes) who underwent successful PVI procedure (at our university clinic) in early follow up period of 30-60 days. An 11-item questionnaire assessed: general health, physical activity, fatigue, dyspnea, palpitations, anxiety/stress, sleep quality, emotional stability, social life, return to work, and overall satisfaction. Data were summarized using frequencies and percentages. Where appropriate, associations were tested using Chi-square or Fisher’s exact test; p < 0.05 was considered statistically significant.

Patient-reported outcomes are summarized in Table 1. Most patients reported improvement or stability in general health (89%; p < 0.001), with 46% "much improved." Physical activity improved in 56% (p = 0.002). Fatigue and dyspnea were rare or absent in 61% and 80%, respectively (p < 0.01). Palpitations were markedly reduced (70% rarely/never; p = 0.003). Anxiety/stress improved in 87% (p < 0.001) and sleep quality in 71% (p = 0.006). Emotional stability ("often" or "always positive") was observed in 78% (p < 0.001), and social activity improved in 71% (p = 0.004). Regarding recovery, 51% returned to daily activities within 2 weeks, and 79% within 3 months. Overall satisfaction was high, with 81% satisfied or very satisfied and 6% dissatisfied (p < 0.001).

Early post PVI follow up period was associated with significant improvements in physical function, psychological well-being, and social participation, with high satisfaction rates and early return to daily activities. These findings support the early significant benefits of PVI on patient-perceived quality of life in routine clinical practice.Table 1.

Patient Outcomes