Pulsed field ablation for the interventional treatment of atrial fibrillation: a scientific statement of the European Heart Rhythm Association of the European Society of Cardiology, the Heart Rhythm Society, the Asia Pacific Heart Rhythm Society, the Latin American Heart Rhythm Society, and the Canadian Heart Rhythm Society
EP Europace Journal
Abstract
Pulsed field ablation has emerged as a novel non-thermal treatment modality with a distinct safety profile for the interventional treatment of atrial fibrillation. By inducing irreversible electroporation, pulsed field ablation achieves myocardial ablation while preserving surrounding structures such as nerves, vasculature, and the oesophagus. This European Heart Rhythm Association of the European Society of Cardiology scientific statement, endorsed by major international societies, reviews the biophysics, technology, clinical evidence, workflow, safety, and training aspects of pulsed field ablation. Randomized trials demonstrate comparable efficacy to radiofrequency and cryoballoon ablation, with advantages in safety and efficiency. The statement provides practical advice for clinical implementation and operator training and identifies key gaps in evidence and priorities for future research and innovation.
Contributors
Antonio Dello Russo
Author
Heiko Lehrmann
Author
Claire Martin
Author
Andrea Natale
Author
Armando Perez-Silva
Author
Jonathan Piccini
Author
Tobias Reichlin
Author
Raphael Rosso
Author
Andrea Sarkozy
Author
Hiroshi Tada
Author
Stylianos Tzeis
Author
Atul Verma
Author
Bradley Wilsmore
Author
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