Two attempts at transcatheter device closure of an acquired Gerbode defect following mitral valve replacement: a case report

European Heart Journal - Case Reports

29 August 2025
Organised by: Logo
ESC Journals HEART FAILURE Chronic Heart Failure IMAGING Echocardiography Interventional Cardiology

Abstract

AbstractBackground

A Gerbode defect, an abnormal communication between the left ventricle and right atrium, is acquired or congenital. A significant Gerbode defect may lead to symptomatic heart failure, requiring closure through surgery or intervention.

Case summary

We present a case of an acquired Gerbode defect in a 47-year-old woman with rheumatic heart disease who underwent a second mitral valve replacement. Postoperatively, heart failure was observed, which was attributed to severe tricuspid valve regurgitation. Subsequently, transthoracic and transoesophageal echocardiography and cardiac magnetic resonance imaging were used to establish a definitive diagnosis. The patient was successfully treated with percutaneous device closure, resulting in complete resolution of her heart failure.

Discussion

Gerbode defects can occur following cardiac surgery and are frequently misdiagnosed as tricuspid regurgitation or pulmonary hypertension. Transcatheter device closure may be a viable treatment option for patients at high risk of reoperation. However, it should be performed at a specialized centre with expertise in cardiac intervention.

Contributors

Thi Minh Ly Nguyen
Thi Minh Ly Nguyen

Author

Hanoi Medical University Hospital Hanoi , Viet Nam