Saw-tooth cardiomyopathy from foetal to neonatal period: a case report and literature review

Saw-tooth cardiomyopathy is a rare condition characterized by left ventricular (LV) dysplasia, defined by multiple myocardial crypts resembling a ‘saw-tooth’ pattern on imaging examinations.

We present a case involving a 10-day-old neonate who was diagnosed with saw-tooth cardiomyopathy, a diagnosis substantiated by echocardiography, computed tomography (CT), and cardiac magnetic resonance imaging (CMR). The patient demonstrated arrhythmia characterized by premature atrial contractions and had a suspected cardiomyopathy identified during the foetal period.

The diagnosis of this condition is solely based on morphological features and may be misdiagnosed as LV non-compaction. Imaging modalities, including echocardiography, CT, and CMR are valuable diagnostic tools. Owing to its rarity and unclear pathogenesis, the prognosis of saw-tooth cardiomyopathy remains uncertain, necessitating long-term, potentially lifelong follow-up.