Physiology of aldosterone and pharmacology of aldosterone blockers
European Heart Journal Supplements
20 May 2011
Organised by: 
Abstract
New adverse effects of aldosterone are now apparent: endothelial dysfunction, myocardial fibrosis and LV remodelling. Aldosterone blockade is able to reverse these adverse effects and so reduce mortality in heart failure. Pharmacological differences between spironolactone and eplerenone are discussed.
Contributors
Allan D. Struthers
Author
University of Dundee Dundee , United Kingdom of Great Britain & Northern Ireland
Thomas Unger
Author
